Misoprostol With Intrauterine Device Insertion

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to see if using misoprostol (a medication that softens the cervix) before placing an intrauterine device for contraception reduces pain in women who have never delivered a baby.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Oregon Health and Science University
• Treatments: Magnesium Oxide; Misoprostol

Criteria

Inclusion Criteria:

• Nulliparous women (defined as those without a history of pregnancy, despite the outcome, beyond 20 weeks gestation)

• Ages 18-45

• Seeking long-term reversible contraception with an intrauterine device (either Mirena or Paraguard) through the OHSU Center for Women's Health and Planned Parenthood of the Columbia Willamette

Exclusion Criteria:

• Pregnancy occurring less than 6 weeks from time of presentation

• History of prior intrauterine device placement

• History of Mullerian tract anomalies

• History of uterine surgery

• Allergy or intolerance to misoprostol or other prostaglandin

• Pelvic inflammatory disease (current or within the past 3 months)

• Sexually transmitted diseases (current)

• Puerperal or postabortion sepsis (current or within the past 3 months)

• Purulent cervicitis (current)

• Undiagnosed abnormal vaginal bleeding

• Malignancy of the genital tract

• Known uterine anomalies or fibroids distorting the cavity in a way incompatible with intrauterine device insertion

• Allergy to any component of the intrauterine device or Wilson's disease (for copper- containing intrauterine device)