Misoprostol Before Hysteroscopy in Infertile Cases
Status:
Unknown status
Trial end date:
2016-05-01
Target enrollment:
Participant gender:
Summary
The role of hysteroscopy in infertility investigation is to detect possible intrauterine
changes that could interfere with implantation or growth or both of the conceptus, with the
invention of miniature hysteroscope, it is possible to perform hysteroscopy in an office
setting (Outpatient hysteroscopy; OH), for diagnostic and certain therapeutic intervention.
It is currently acknowledged as the 'gold standard' investigation of the intrauterine
abnormalities.
Cervical priming prior to diagnostic hysteroscopy softens the cervix and lessens the force
needed for dilation, thereby potentially reducing the probability of procedural complication
such as uterine perforation, cervical laceration, failure to dilate, and creation of a false
track that can occur during cervical entry.
Misoprostol is a prostaglandin El analogue, that can be administered either orally or
vaginally, that can cause cervical ripening by inducing collagenolytic activity and synthesis
of proteoglycans.