Overview

Mismatched Transplantation Using High-dose Post-transplant Cyclophosphamide

Status:
Completed
Trial end date:
2017-10-05
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to learn about the safety of giving a stem cell transplant from a tissue-mismatched donor, followed by cyclophosphamide, to patients with certain types of blood disorders or blood cancers. Melphalan, thiotepa, and fludarabine will also be given before the transplant. Researchers will study the health status of these patients at 3 months after the transplant.
Phase:
Phase 2
Details
Lead Sponsor:
M.D. Anderson Cancer Center
Treatments:
Cyclophosphamide
Fludarabine
Fludarabine phosphate
Lenograstim
Melphalan
Mesna
Mycophenolate mofetil
Mycophenolic Acid
Rituximab
Tacrolimus
Thiotepa
Vidarabine