Minto Model in Effect Site Mode for Target-Controlled Infusion of Remifentanil During Cardiopulmonary Bypass
Status:
Completed
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Target controlled infusion with remifentanil is widely used during cardiac surgery, wich is
performed using the Minto model. It was derived from patients undergoing general surgery.
However, pharmacokinetics of remifentanil can be changed during cardiopulmonary bypass. The
investigators tested whether Minto model for target controlled infusion produces constant
plasma remifentanil concentration during the cardiac surgery.