Minocycline for the Prevention of Post-operative Intercostal Neuralgia
Status:
Unknown status
Trial end date:
2014-02-01
Target enrollment:
Participant gender:
Summary
In about half the patients who have an open chest surgery there is persistent severe pain in
the chest. The investigators are examining whether minocycline, a commonly used antibiotic,
will prevent pain. Minocycline blocks the activity of immune cells which the investigators
believe are responsible for prolonging the pain.