Minimum Effective Dose of Ropivacaine for Spinal Anesthesia for Cesarean Delivery

• Status: Completed
• Trial end date: 2017-06-30
• Target enrollment: 0
• Participant gender: Female

Summary

Ropivacaine is one of commonly used anesthetics for spinal anesthesia. Usually L2-3 or L3-4 intervertebral space is chosen for spinal anesthesia. The efficacy of ropivacaine injected into subarachnoid space depends on the given dose and the chosen intervertebral space. Appropriate dose could satisfy the requirement of operation and reduce incidence of the adverse reaction. But it is not certain about the minimum effective dose of ropivacaine in cesarean section through the two intervertebral spaces, respectively. This study is being conducted to find the minimum effective doses for L2-3 and L3-4 spinal anesthesia in cesarean section.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Shanghai 6th People's Hospital
• Treatments: Ropivacaine

Criteria

Inclusion Criteria:

• Full term parturient(> 37 and <42 weeks gestation)

• Above 20 years and below 35 years

• American Society of Anesthetists(ASA) I to II

• Singleton pregnancy

• Elective cesarean section

• Body weight during 60-85kg, height during 150-170cm

Exclusion Criteria:

• Patient refusal

• Hypertension

• Diabetes mellitus

• Heart diseases

• Asthma

• Abnormal fetus or placenta

• Contraindications to combined spinal-epidural anesthesia(CSEA)

• Allergy to ropivacaine