Minimum Effective Concentration of Bupivacaine in Ultrasound-guided Axillary Brachial Plexus Block
Status:
Completed
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
Background: The use of ultrasound in regional anesthesia enables a reduction in the local
anesthetic volume. The present study aimed to determine the minimum effective concentration
(EC50 and EC95) of bupivacaine for axillary brachial plexus block (ABPB). Methods: Following
approval by the Research Ethics Committee, patients with a physical condition of I or II
according to the American Society of Anesthesiologists, between 21 and 65 years of age were
recruited and subjected to elective surgery of the hand and ABPB. The concentration of the
anesthetic was determined using a step-up/step-down method and was based on the outcome of
the preceding block.