Military COVID-19 Hydroxychloroquine Pre-exposure and Post-exposure Prophylaxis Study
Status:
Not yet recruiting
Trial end date:
2020-08-01
Target enrollment:
Participant gender:
Summary
There is significant interest throughout the United States in performing a well-designed
study to evaluate whether there is value in using Hydroxychloroquine or Chloroquine as a
pre-exposure prophylaxis or post-exposure prophylaxis regimen for COVID-19 patients and at
risk personnel.
We have designed a prospective double blinded randomized controlled clinical trial to answer
just this question.
The study will consist of 4 arms:
1. A placebo control arm of 450 patients
2. A low dose prophylaxis arm of 450 patients treated with 200mg Hydroxychloroquine daily
3. A high dose prophylaxis arm of 450 patients treated with 400mg Hydroxychloroquine daily
4. A post-exposure arm of 100 patients treated with 400mg Hydroxychloroquine daily for 7
days.