Mild Hypothermia and Supplemental Magnesium Sulfate Infusion in Severe Traumatic Brain Injury (TBI) Subjects
Status:
Terminated
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
The investigators hypothesize that hypothermia (body cooling) and additional magnesium
sulfate will improve the outcome of severe Traumatic Brain Injury (TBI) patients.
This is a study to compare the outcomes of patients with severe traumatic brain injury who
have been allocated to one of the following three groups:
Group 1 - Conventional therapy following traumatic brain injury Group 2 - Subjects will have
their core body temperature lowered to 34C Group 3 - Subjects will have their core body
temperature lowered to 34C and will receive a supplemental intravenous infusion of magnesium
sulfate.