Mifepristone and Mid-Trimester Termination of Pregnancy
Status:
Completed
Trial end date:
2006-11-01
Target enrollment:
Participant gender:
Summary
Mid-second trimester medical terminations of pregnancy require admission to the hospital for
the length of time it takes a woman to abort. The current protocol at BMC uses intra-amniotic
digoxin injection the day prior to admission. The following day, the woman is admitted and
given sequential doses of misoprostol until delivery occurs. The average length of time
between the first dose of misoprostol and delivery is 12 hours, requiring most women to stay
overnight. This is a randomized, placebo-controlled, double-blinded study designed to
determine whether adding mifepristone significantly reduces the induction interval time (time
between starting the first misoprostol and delivery) required for a second trimester
termination.