Midodrine and Albumin for Cirrhotic Patients With Functional Renal Impairment

• Status: Completed
• Trial end date: 2016-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The objective of the study was evaluate the effect of administration of midodrine and albumin on renal function in patients with cirrhosis and creatinine greater than 1,2mg/dl.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Clinic of Barcelona
• Treatments: Midodrine

Criteria

Inclusion Criteria:

• Liver Cirrhosis

• Serum Creatinine greater than 1,2 mg/dL

• to have given written informed consent

Exclusion Criteria:

• pregnancy

• Systolic blood pressure above 150mmHg and/or diastolic blood pressure above 90mmHg

• Previous treatment with transjugular intrahepatic portosystemic shunt (TIPS) or surgical shunts

• Antibiotic treatment in the previous 7 days before inclusion, except for prophylaxis of spontaneous bacterial peritonitis

• infection by HIV

• contraindications for albumin and/or midodrine use