Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve
Status:
Terminated
Trial end date:
2019-03-31
Target enrollment:
Participant gender:
Summary
The aim of this study is to assess microvascular function as determined by a cardiovascular
magnetic resonance measurement of whole-heart (global) perfusion reserve. The goal is to
determine the prevalence of MVD in two common forms of non-ischemic cardiomyopathy,
hypertrophic cardiomyopathy (HCM) and idiopathic dilated cardiomyopathy (IDCM). The
hypothesis that an optimized technique will provide robust detection of MVD and that a
multifaceted approach will provide new insights into the pathophysiology of MVD, including
the influence of myocardial scarring upon the presence and severity of MVD.