Microcirculatory Impairment in Patients With Leprosy
Status:
Completed
Trial end date:
2010-02-01
Target enrollment:
Participant gender:
Summary
In this study the investigators have aimed to evaluate morphology and reactivity of cutaneous
microcirculation in patients with lepromatous leprosy. Ten patients, without any other
comorbidity were compared to ten controls without leprosy or any other comorbidity, using the
Cytoscan® [orthogonal polarization spectral (OPS) imaging], Fourier analysis of laser Doppler
signal to evaluate vasomotion (rhythmic spontaneous oscillation of arteriolar diameter) and
laser Doppler flowmetry associated to iontophoresis of vasoactive substances (acetylcholine
and sodium nitroprusside).