Microbial Colonization and Change of Chronic Keratinized Hand Eczema After Using Halometasone Triclosan

• Status: Completed
• Trial end date: 2017-12-08
• Target enrollment: 0
• Participant gender: All

Summary

The clinical study of the microbial colonization of chronic keratinized hand eczema and the change of microbial colonization after external using of Halometasone Triclosan Cream

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beijing Friendship Hospital
• Treatments: Betamethasone; Halometasone; Triclosan

Criteria

Inclusion Criteria:

• Age ≥ 18 years

• Chronic Keratinized hand eczema for at least 3 months

• The affected area is greater than 30%

• Overall assessment of the severity of the disease(IGA)≥3 OR HEES≥13

• No obvious incentive .Who have read the instructions of the subject, agreed to and signed written informed consent, and have been able to provide a personal medical history.

Exclusion Criteria:

• Pregnancy, breast feeding

• Severe liver and kidney disease, blood system disease, autoimmune disease, chronic severe infection, diabetes, mental illness, drug use, alcohol abuse, etc

• Malignant neoplasms or other serious maladies that may affect the correct assessment of efficacy

• Topical corticosteroid was suspended for less than 2 weeks;The system used corticosteroids and other immunosuppressive agents (thunder vine and other drugs) which were suspended for less than four weeks

• Eczema of the facial and skin creases

• Atopic dermatitis, contact dermatitis, blister hand eczema, contact urticaria, discoid eczema

• participated in other clinical trials within 3 months.

• Known sensitivity to Halometasone Triclosan

• failure to follow the prescribed medication or the incomplete record of the test process which will affect the curative effect judgment

• Other reasons why researchers think they should not be included