MicroRNA Expression in Everolimus-based Versus Tacrolimus-based Regimens in Kidney Transplantation
Status:
Unknown status
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
The calcineurin inhibitor drugs including cyclosporin and tacrolimus are well-known as
nephrotoxicity. However, these drugs are essential for kidney transplant especially in high
immunological risks. To date, however, there is an alternative regimen by using of
everolimus-based which showing less toxicity than tacrolimus-based regimen by its mechanisms.
Of note, this study aims to evaluate the toxicity by using microRNA profiles detection
between everolimus-based and tacrolimus-based immunosuppressive regimen in kidney
transplantation.