Metronidazole as an Adjunct of Non- Surgical Treatment of Peri-implantitis
Status:
Completed
Trial end date:
2020-12-22
Target enrollment:
Participant gender:
Summary
The use of systemic antibiotics as and adjunct to non-surgical peri-implant therapy may be an
improvement in comparison to these therapies alone. The primary objective is the evaluation
of significant changes in probing pocket depth between non-surgical with or without
antibiotics.
This is a controlled-placebo clinical trial design. Patients with osseointegrated oral
implants will be selected and recruited from a university clinic. Oral hygiene instruction
and non-surgical debridement at implants will be provided with ultrasonic devices and
immediately after, patients will be prescribed:
Group Control: A placebo with the same characteristics as the antibiotic Group Test: Systemic
antibiotics (Metronidazole 250mg, 2 capsules three times a day, for 7 days Three and six
months after non-surgical treatment, clinical parameters will be registered and radiographs
compared using reproducible landmarks. Any adverse event will be also recorded.