Metoclopramide vs Placebo for Prevention of Pneumonia in Acute Stroke
Status:
Completed
Trial end date:
2021-10-02
Target enrollment:
Participant gender:
Summary
Pneumonia is a major cause of mortality and morbidity in patients with acute stroke fed via
nasogastric tubes and may be because of vomiting and gastro-esophageal regurgitation. The aim
of the study was to assess whether regular treatment with metoclopramide, a D2-receptor
antagonist with antiemetic and gastric prokinetic actions, could reduce the rate of
pneumonia.