Methylprednisolone Versus Dexamethasone in Pediatric Caudal Block
Status:
Not yet recruiting
Trial end date:
2023-12-01
Target enrollment:
Participant gender:
Summary
This randomized, double-blind, controlled bi-center study was designed to compare the
postoperative analgesic efficacy of dexamethasone and methylprednisolone in caudal block for
children undergoing hypospadias surgical repair using the duration of analgesia as the
primary outcome. We hypothesize that methylprednisolone will provide superior postoperative
analgesia than dexamethasone when added to bupivacaine for caudal block. This study will be
conducted on 80 male patients of American Society of Anesthesiologists physical status I-II
of with their age ranging from 1 to 6 years scheduled for surgical repair of hypospadias. The
patients will be randomly assigned into 2 groups:- Group D: will receive 0.5 ml/kg volume
(bupivacaine 0.25 % + dexamethasone 0.1mg/kg) Group M: will receive 0.5 ml/kg volume
(bupivacaine 0.25% + methylprednisolone 0.5mg/kg) The main collected data will be the
duration of analgesia (first need for rescue analgesia ), the severity of postoperative pain
according to FLACC and the side effects like nausea and vomiting, respiratory depression.