Overview

Methotrexate or Thiotepa Combined With R-CHOP and Orelabrutinib in CNSL Patients

Status:
NOT_YET_RECRUITING
Trial end date:
2028-11-01
Target enrollment:
Participant gender:
Summary
This study is designed as an open-label, prospective, single-arm, single-center trial aimed at evaluating the efficacy and safety of MTX or Thiotepa combined with Orelabrutinib and standard chemotherapy regimens in the treatment of DLBCL patients with central nervous system involvement.
Phase:
PHASE2
Details
Lead Sponsor:
Ruijin Hospital
Treatments:
orelabrutinib
Thiotepa