Overview

Methotrexate and Thiotepa in Treating Patients With Newly Diagnosed Primary CNS Lymphoma

Status:
Completed
Trial end date:
2006-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as methotrexate and thiotepa, work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining methotrexate with thiotepa in treating patients who have newly-diagnosed primary CNS lymphoma.
Phase:
Phase 2
Details
Lead Sponsor:
New Approaches to Brain Tumor Therapy Consortium
Collaborator:
National Cancer Institute (NCI)
Treatments:
Calcium
Leucovorin
Levoleucovorin
Methotrexate
Thiotepa