Overview

Methotrexate and Mycophenolate Mofetil for UVEITIS

Status:
Completed
Trial end date:
2018-08-09
Target enrollment:
Participant gender:
Summary
In the First-line Antimetabolites as Steroid-sparing Treatment (FAST) Uveitis Trial, the investigators propose to establish which immunosuppressive therapy, methotrexate or mycophenolate mofetil, is more effective as a first-line, corticosteroid-sparing agent for the treatment of non-infectious uveitis in a block-randomized, observer-masked, comparative effectiveness trial.
Phase:
Phase 3
Details
Lead Sponsor:
University of California, San Francisco
Collaborators:
Aravind Eye Hospitals, India
Asociación para Evitar la Ceguera en México
King Khaled Eye Specialist Hospital
National Eye Institute (NEI)
Northwestern University
Oregon Health and Science University
Royal Victoria Eye and Ear Hospital
Treatments:
Antimetabolites
Methotrexate
Mycophenolate mofetil
Mycophenolic Acid
Prednisone