Methotrexate Compared With Paclitaxel in Treating Patients With Advanced Head and Neck Cancer
Status:
Completed
Trial end date:
2004-03-02
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. It is not yet known whether methotrexate or paclitaxel is more
effective in treating patients with advanced head and neck cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of methotrexate with that of
paclitaxel in treating patients who have advanced head and neck cancer that cannot be treated
with cisplatin.