Overview

Methacholine, Long-acting M-cholinolytic and beta2-agonist on the Activity of Beta-receptors in Healthy Volunteers

Status:
Unknown status

Trial end date:
2020-10-01

Target enrollment:

Participant gender:

Summary

Interventional open-labeled study in parallel groups is aimed to evaluate changes of beta receptors in healthy volunteers under the influence of inhaled metacholine, long-acting anticholinergics and beta-agonists using modified radioligand method.

Phase:

N/A

Details

Lead Sponsor:

Federal State Budgetary Institution, Pulmonology Scientific Research Institute

Collaborators:

Branch of Shemyakin-Ovchinnikov Institute of Bioorganic chemistry of RAS
Moscow State University of Medicine and Dentistry
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation

Treatments:

Bromides
Cholinergic Antagonists
Formoterol Fumarate
Methacholine Chloride
Tiotropium Bromide