Metformin to Treat Corticosteroids-induced Hyperglycemia
Status:
Recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
Antenatal corticosteroids, particularly, betamethasone is routinely administered to pregnant
women at risk for preterm delivery to improve neonatal outcomes.
Although antenatal betamethasone was shown to induce both maternal hyperglycemia and neonatal
hypoglycemia, to date, there is insufficient data to establish whether treatment for maternal
hyperglycemia, particularly, metformin, will decrease the risk for neonatal hypoglycemia,
particularly of preterm neonates.
In the present study the investigators will examine the effect of treatment with metformin on
maternal glycemic control and hypoglycemia in preterm neonates following maternal
betamethasone treatment.