Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization

• Status: Terminated
• Trial end date: 2011-03-01
• Target enrollment: 0
• Participant gender: Female

Summary

Metformin should be administered with caution and could be potentially dangerous in infertile patients with PCOS who show a poor ovarian response and are undergoing gonadotropin-based ovarian stimulation. However, data that address this point are totally lacking.

On the basis of these considerations, the aim of the current clinical trial was to test the hypothesis that metformin reduces the ovarian response in infertile patients with PCOS who have a potentially poor ovarian response and who undergo gonadotropin stimulation for IVF cycles.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Magna Graecia
• Treatments: Metformin

Criteria

Inclusion Criteria:

• PCOS

• Prognosis for poor response

• Infertility

Exclusion Criteria:

• Male factor infertility

• Tubal infertility