Metformin in Patients With PCOS and Predictors of Poor Ovarian Response Ongoing In-vitro Fertilization
Status:
Terminated
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
Metformin should be administered with caution and could be potentially dangerous in infertile
patients with PCOS who show a poor ovarian response and are undergoing gonadotropin-based
ovarian stimulation. However, data that address this point are totally lacking.
On the basis of these considerations, the aim of the current clinical trial was to test the
hypothesis that metformin reduces the ovarian response in infertile patients with PCOS who
have a potentially poor ovarian response and who undergo gonadotropin stimulation for IVF
cycles.