Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome

• Status: Unknown status
• Trial end date: 2016-09-01
• Target enrollment: 0
• Participant gender: Female

Summary

Randomized, placebo controlled clinical trial that evaluate the role of taking metformin therapy during pregnancy in women with polycystic ovarian syndrome(PCOS) in reducing the development of gestational diabetes(GDM) and improving pregnancy outcomes.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ain Shams University
• Treatments: Folic Acid; Metformin; Vitamin B Complex

Criteria

Inclusion Criteria:

• All women had confirmed diagnosis of PCOS before pregnancy according to revised 2003 Rotterdam criteria.

• Age more than 20 and more than 40 years.

• BMI ranging from (25_35 )

• Written and signed informed consent is given from the patient to participate in the study.

Exclusion Criteria:

• Women with pre-gestational diabetes mellitus confirmed by 2hrs OGTT.

• Patients who take metformin in the first 12 wk of pregnancy.

• Patients who are unwilling to participate in the study.