Overview

Metformin and Muscle in Insulin-resistant Older Veterans

Status:
Completed
Trial end date:
2018-08-31
Target enrollment:
Participant gender:
Summary
Sarcopenia is the loss of muscle mass, strength and function with aging and is associated with increased disability, falls and fractures. Older adults with diabetes and prediabetes are insulin resistant and have a higher risk of developing sarcopenia. This study examines the use of metformin, an antidiabetic drug, for preventing the development of sarcopenia in older adults with prediabetes.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
VA Office of Research and Development
Collaborator:
Oregon Health and Science University
Treatments:
Insulin
Metformin