Metformin and Core Temperature in Obese and Lean Males
Status:
Completed
Trial end date:
2016-06-01
Target enrollment:
Participant gender:
Summary
Metformin is known to increase 18F-FDG uptake in subjects using metformin in retrospective
trials.
In this study the researchers aim to investigate the influence of metformin (500 mg 1/day) on
temperature in the colon, glucose uptake in the colon and energy expenditure in healthy lean
(BMI < 24kg/m2) or obese subjects (BMI>28kg/m2). The investigators will measure 18F-FDG
uptake in the colon, temperature in the colon, insulin sensitivity and energy expenditure
before after using metformin.
Phase:
N/A
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)