Overview

Metformin Effect on Fracture Healing in Post-Menopausal Women

Status:
Completed
Trial end date:
2021-01-01
Target enrollment:
0
Participant gender:
Female
Summary
study the effect of metformin drug on fracture healing of patients with high risk of delayed fracture healing or non-union and correlating this to serum irisin myokine level.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Damanhour University
Treatments:
Metformin
Criteria
Inclusion Criteria:

- Age range from 55 to less than 65 years old with bone fracture.

Exclusion Criteria:

- Age equal or less than 55 years

- Age equal or more than 65 years

- Unstable or hospitalized patients with heart failure

- Hepatic impairment

- Chronic kidney disease with eGFR <45 mL/minute/1.73 m2

- Open fractures

- Pathological fractures

- Diabetic patients