Meta-analysis of Orlistat Laboratory Data From Placebo-controlled Clinical Trials
Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
Roche and GSK will carry out a meta-analysis of liver function data from trials of orlistat
to establish whether there is any indication of liver toxicity. The motivation is a
cumulative assessment of drug-induced liver injury (DILI) conducted by the FDA following
spontaneous reports of liver toxicity in people taking Xenical or Alli.