Overview

Memory Modulation by Pain During Anesthesia

Status:
Completed
Trial end date:
2018-12-12
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the effects of pain on facilitating long-term auditory memory in the presence and absence of distinct intravenous anesthetics. The ability to identify previously presented words from a list assessed the degree of memory formation. In a subset of subjects, functional magnetic resonance imaging was used to identify the neural correlates of memory inhibition or facilitation by the combination of pain and anesthetic used.
Phase:
Phase 1
Details
Lead Sponsor:
University of Pittsburgh
Collaborator:
Foundation for Anesthesia Education and Research
Treatments:
Dexmedetomidine
Ketamine
Midazolam