Memory Consolidation in Pharmacologically Enhanced Naps

• Status: Completed
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will examine whether various drugs affecting sleep cycles can improve different kinds of memory.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of California, San Diego
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Sodium Oxybate; Zolpidem

Criteria

Inclusion Criteria:

• Speaks English

• Resides in the general San Diego community

• Completed at least 12 years of formal education, because education may affect performance on the cognitive task

Exclusion Criteria:

• No regular sleep-wake schedule, defined as not meeting study criteria or scoring between 31 and 69 on the Horne-Ostberg Morningness-Eveningness Questionnaire

• Presence of a sleep disorder reported or detected on the questionnaires

• Personal or immediate family (i.e., first degree relative) history of diagnosed significant psychopathology

• Personal history of head injury with loss of consciousness for more than 15 minutes or with seizures

• History of substance dependence

• Current use of any psychotropic medications

• Any cardiac, respiratory, or other medical condition that may affect cerebral metabolism

• Noncorrectable vision and audition impairments