Memantine (10mg BID) for the Frontal and Temporal Subtypes of Frontotemporal Dementia
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
The primary objective of the study is to determine whether memantine is effective in slowing
the rate of behavioral decline in frontotemporal dementia.
The secondary objective of the study is to assess the safety and tolerability of long-term
treatment with memantine in patients with frontotemporal dementia (FTD) or semantic dementia
(SD). To determine whether memantine is effective in slowing the rate of cognitive decline in
frontotemporal dementia. To evaluate whether memantine delays or decreases the emergence of
parkinsonism in frontotemporal dementia.
The tertiary objective of the study is to determine whether treatment with memantine affects
changes in weight