Melatonin Use in the Intensive Care Elderly Population

• Status: Unknown status
• Trial end date: 2018-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators are studying the use of Melatonin in non-ventilated patients over the age of 65. Primary endpoint will be assesments of delirium, with secondary endpoints to include length of stay, use of anti-psychotic medications, and mortality

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: MICE Trial Group
• Treatments: Melatonin

Criteria

Inclusion Criteria:

• Non-ventilated Patients over the age of 65

Exclusion Criteria:

• Patients with head trauma or Neurosurgical intervention

• Patients <65 years of age

• Patients with an expected life expectancy <48 hours

• Blind patients

• Patients with a seizure history

• Patients with uncontrolled hypertension

• Patients with a supratheraputic (>3.0) INR

• Patients on strong CYP1A2 inhibitors: ciprofloxacin, fluvoxamine, methoxsalen, ofloxacin, primaquine

• Patients who do not speak English or Spanish