Melatonin Premedication in Children Undergoing Surgery
Status:
Completed
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
Melatonin has been proposed as alternative to midazolam as a premedication in procedures
preceding anaesthesia induction. The objective of this prospective, randomized, double-blind
study is to investigate the possible effect of melatonin premedication on the required
infusion of propofol in comparison to midazolam, evaluating the efficacy of oral melatonin on
sedation in children undergoing surgery.
Preoperative anxiety and postoperative analgesia are also assessed in both groups.