Melatonin Intervention For Neurocognitive Deficits in the St. Jude Lifetime Cohort
Status:
Completed
Trial end date:
2017-04-19
Target enrollment:
Participant gender:
Summary
Primary objective:
1. To examine the efficacy of melatonin treatment on neurocognitive functioning in adult
survivors of childhood cancer.
Secondary objectives:
1. To evaluate the efficacy of melatonin treatment on delayed sleep onset latency in
long-term childhood cancer survivors.
2. To investigate whether improvement in sleep onset latency due to melatonin treatment is
associated with neurocognitive improvement in long-term childhood cancer survivors.
This study is a randomized double-blind placebo controlled trial of time release melatonin
for adult survivors of childhood cancer who demonstrate impaired neurocognitive functioning
and/or difficulty falling asleep.