Medication Adherence Therapy for Opioid Abusing Pain Patients

• Status: Completed
• Trial end date: 2005-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to develop and pilot test a combined behavioral and pharmacological intervention designed to decrease pain, functional interference, and drug abuse while increasing medication adherence.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Treatments: Methadone

Criteria

Inclusion Criteria:

• Uninterrupted pain of at least 6 months duration

• Pain is continuous, rather than intermittent

• Pain in the severe range (VAS = 7-10) while medicated

• Poor response to non-pharmacological interventions for pain (if appropriate)

• One or more of the following pain diagnoses: (a) back/neck pain; (b) myofacial pain; (c) neuropathic pain (e.g., diabetic or AIDS neuropathy, Complex regional pain syndrome); (d) arthritic pain; (e) MS; or (f) sickle cell (must meet chronicity criteria)

• Evidence of tolerance/physiological dependence on opioid analgesics

• Current opioid use disorder (DSM-IV criteria)

• Continuous use of opioid analgesics for a minimum of 6 months prior to referral. [Note: This is consistent with minimum 6-month requirement for diagnosis of chronic pain].

• Minimum of 2 signs/symptoms of medication mismanagement identified by the Referring MD (PROBLEMS WITH PAIN MEDS checklist)

Exclusion Criteria:

• Please contact site regarding exclusion criteria for this study.