Overview

Median Effective Dose of Dexmedetomidine in Elective Upper Limb Lidocaine Intravenous Regional Anesthesia

Status:
Completed
Trial end date:
2020-03-01
Target enrollment:
0
Participant gender:
All
Summary
Auxiliary drugs augment the effect of local anesthetic in intravenous regional anesthesia (IVRA). The purpose of our study was to estimate the median effective dose (ED50) of Dexmedetomidine in elective upper limb Lidocaine 0.5% IVRA.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
South Valley University
Collaborator:
Tanta University
Treatments:
Anesthetics
Dexmedetomidine
Lidocaine
Criteria
Inclusion Criteria:

- Aged between 18 and 60 years

- American Society of Anesthesiologists physical status I or II

- Undergoing minor upper limb orthopedic surgical procedures in the hand, wrist and
forearms including: metacarpal fracture, tendon injury, and carpal tunnel release.

Exclusion Criteria:

- Allergy to test drugs.

- vascular disease.

- contraindication to tourniquet applications.

- difficulty to manipulate the surgical limb.

- surgery expected to last more than an hour.

- patient refusal