Meclofenamate in Subjects With Recurrent or Progressive Brain Metastasis From Solid Tumor Primary
Status:
Active, not recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
Cancer that has spread to the brain, or brain metastasis, is difficult to treat.
Meclofenamate is a drug which has been shown to reduce brain metastasis growth in the
laboratory. This medicine has been used in the past to treat pain. But, in this study, it
will be used to prevent new brain metastasis. This is the first time that meclofenamate will
be used in patients with brain metastasis.
This is a pilot study which means that the purpose of this study is to determine if a larger
clinical trial of meclofenamate is possible in patients with brain metastasis. This study
also aims to find out what effects, good and/or bad meclofenamate has on the patient and the
cancer that has spread to the brain. The investigators also want to learn more about
potential effects that this drug may have in the digestive system.