Mechanisms Responsible for Cardiac and Skeletal Muscle Energetic Impairment in Diabetes
Status:
Unknown status
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
Diabetes increases the risk of heart failure. This is mainly due to a disease of the blood
vessels supplying the heart muscle and/or high blood pressure, but abnormal metabolism may
also contribute. We plan to study the mechanisms involved in this abnormal metabolism, whilst
also assessing the effects of a drug called Perhexiline which improves the abnormal
metabolism that is present in diabetic patients before the development of heart failure.