Overview

Mechanism(s) Underlying Cardiovascular Effects of ARB/NEP Inhibition - Aim 2

Status:
Withdrawn
Trial end date:
2020-01-01
Target enrollment:
Participant gender:
Summary
This study tests the hypothesis that endogenous bradykinin contributes to effects of a combined angiotensin receptor blocker/neprilysin inhibitor (LCZ696 or Entresto)
Phase:
Phase 2
Details
Lead Sponsor:
Vanderbilt University Medical Center
Treatments:
Enalapril
Enalaprilat
Icatibant
LCZ 696
Sacubitril and valsartan sodium hydrate drug combination
Valsartan