Mechanism-based Choice of Therapy for Pain: Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile?

• Status: Completed
• Trial end date: 2014-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Mechanism-based choice of therapy for pain:

Can successful prevention of migraine be coupled to a psychophysical pain modulation profile?

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rambam Health Care Campus
• Treatments: Amitriptyline; Amitriptyline, perphenazine drug combination; Topiramate

Criteria

Inclusion Criteria:

• female and male migraine patients with a number of month attacks ≥ 4,

• age 18-75,

• without any other chronic pain.

Exclusion Criteria:

• any migraine preventive treatment for last 6 month & psychiatric,

• language or cognitive dysfunction precluding use of psychophysics.