Overview

Mechanism-based Choice of Therapy: Can Treatments Success in Fibromyalgia Patients be Coupled to Psychophysical Pain Modulation Profile?

Status:
Unknown status

Trial end date:
2013-01-01

Target enrollment:

Participant gender:

Summary

Hypothesis: Response to therapy in fibromyalgia can be improved by coupling of specific medications to the individual patterns of dysfunctional pain modulation. Individuals exhibit wide range of pain modulating capabilities that can be assessed by dynamic psychophysical testing. Those that exhibit less efficient endogenous analgesia and/or increased pain summation are known to be more prone to suffer from pain. Tailoring medications to compensate for the specific dysfunctioning modulatory mechanism will improve pain control.

Phase:

N/A

Details

Lead Sponsor:

Tel-Aviv Sourasky Medical Center

Collaborators:

Rambam Health Care Campus
University of California, Davis

Treatments:

Duloxetine Hydrochloride
Pregabalin