Overview

Measuring Blood Flow in the Brain After Epileptic Activity

Status:
Recruiting
Trial end date:
2022-10-01
Target enrollment:
Participant gender:
Summary
In this clinical trial, postictal phenomena (i.e., headache, delirium) will be investigated after administration of acetaminophen and nimodipine in depressed patients receiving electroconvulsive therapy (ECT). Postictal phenomena are thought to result from decreased cerebral blood flow and decreased oxygen concentration in the brain. It is expected that acetaminophen and nimodipine will reduce these postictal phenomena, compared to no treatment, because they target these mechanisms.
Phase:
Phase 2
Details
Lead Sponsor:
Rijnstate Hospital
Collaborators:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Amsterdam University Medical Center
University of Twente
Treatments:
Acetaminophen
Nimodipine