Measurement of Bispectral Index and Awareness in Patients Undergoing Electrophysiology Studies With Isoproterenol
Status:
Completed
Trial end date:
2011-10-01
Target enrollment:
Participant gender:
Summary
Isoproterenol is used as a cardiac stimulant in electrophysiology studies (EP). Preliminary
data suggests that administration of isoproterenol increases the Bispectral index (BIS). BIS
is used to monitor neuronal signals under anesthesia. The BIS level is suggested to
correspond to the level of consciousness. We hypothesize that isoproterenol increases BIS
values because it increases the patient's level of consciousness through its central nervous
system (CNS) stimulatory effects. In this study, we will administer increasing doses of
isoproterenol to EPS patients. We will measure the BIS levels continuously before and after
isoproterenol administration. In addition, we will test the level of awareness of patients by
their response to a modified isolated forearm technique.
Phase:
N/A
Details
Lead Sponsor:
New York University School of Medicine NYU Langone Health