Since antiquity, honey has been recognized for its healing properties. Literature about the
use of medicinal honey for wound care dates back centuries with recent data suggesting its
use in patients suffering from burns or pressure ulcers. Research has shown Manuka honey
(Leptospermum scoparium) to have significant immune benefits and the ability to influence
all phases of wound healing: inflammation, proliferation and remodeling. In addition,
numerous clinical studies have identified positive benefits for wound healing. However,
there is a lack of prospective, randomized controlled data on the use of honey as a
medicinal agent in local wound care and scar healing.
In order to better understand Manuka Honey's ability to aid in healing, the investigators
are conducting a randomized, controlled, single-blinded study of patients undergoing
reconstructive surgery. This project uses split thickness skin graft and free tissue
transfer donor sites as standard wound models to compare the effects of Manuka Honey versus
standard wound care therapies. Through the use of standard wound model and objective
measurement tools, the investigators hope to better elucidate any benefits of this novel
wound care 'technology.'