Manidipine Versus Amlodipine in Patients With Hypertension
Status:
Terminated
Trial end date:
2019-08-14
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate the effect of a third-generation Calcium Channel
Blocker (CCB), manidipine, compared with second-generation Calcium Channel Blocker (CCB),
amlodipine, on the development of peripheral edema using Direct Segmental Multi-Frequency
Bioelectrical Impedance Analysis (DSM-BIA) method in patients with mild to moderate essential
hypertension. Investigator expects this study could show more objective evidence of better
safety of manidipine compared with amlodipine for peripheral edema.