Managing Alcoholism in People Who Do Not Respond to Naltrexone
Status:
Completed
Trial end date:
2008-07-01
Target enrollment:
Participant gender:
Summary
This is a study involving treatment for alcohol dependence (alcoholism). The study will
combine motivational enhancement therapy and cognitive behavioral therapy (combined
behavioral intervention, or CBI) and tests the benefits of continued/discontinued treatment
with naltrexone in a randomized placebo-controlled trial. CBI may have advantages in
motivating patients to greater medication adherence and may address psychosocial factors that
may limit the effects of naltrexone.