Management of the Idiopathic Overactive Bladder With Botulinum Toxin: Systematic Review
Status:
Unknown status
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
Overactive bladder is defined as a syndrome composed of urgency, increased urinary frequency,
and sometimes urinary incontinence; its etiology may be characterized as neurogenic or
non-neurogenic (i.e., idiopathic). This illness has a great impact in quality of life and one
of the available treatments is the injection of Botulinum Toxin. This study aims to review
the efficacy and safety of type-A Botulinum Toxin in the management of Idiopathic Overactive
Bladder. A systematic search was performed in MEDLINE, EMBASE, CENTRAL and LILACS, and the
controlled randomized clinical trials were chosen to review with the CONSORT criteria by
independent reviewers. Outcomes analyzed were the efficacy of the intervention for relieving
the symptoms (urgency, frequency and urgency incontinence), adverse events to treatment,
change in quality of life and urodynamic measures.