Overview

Management of Tunneled Catheter Thrombosis in Hemodialysis Patients: Prospective Study From Qatar

Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
0
Participant gender:
All
Summary
Goal of the study: A- To find out the best protocol for catheter lock solution to decrease the prevalence of catheter thrombosis 1. - The time to first episode of catheter thrombosis lead to catheter change. 2. - Number of acute episode of thrombosis that interrupt dialysis 3. - Median Survival life of the catheter in both groups after adjusting it to the outcome. B- Specific Objective: To evaluate the cost effectiveness by measure 1- Amount of r-TPA used in each group to treatment acute catheter thrombosis 2- Number of catheter exchange in both group 3- Hospitalization days related to catheter malfunctioning or CRI in each group 4- Type and days of antibiotics 5- Cost of the treatment in each group c- Secondary Objective: To correlate the result of two catheters lock solution protocols with the published data using r-TPA instead of heparin once week as compared with heparin 3 times per week as a locking solution.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Hamad Medical Corporation
Criteria
Inclusion Criteria:

- 1- Adult patients aged>14 years 2- Undergoing HD through tunneled HD 3- Recently
inserted or old tunneled catheter 4- Blood flow rate at the beginning of the study≥
300ml/min

Exclusion Criteria:

- 1- Malfunctioning catheter defined by blood flow rate < 300ml/min 2- Known patient to
have allergy to drug medication 3- Major Hemorrhage in previous 4 week